|Other Names||tRNA-specific adenosine deaminase 1, hADAT1, tRNA-specific adenosine-37 deaminase, ADAT1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Specifically deaminates adenosine-37 to inosine in tRNA- Ala.|
|Tissue Location||Ubiquitously expressed.|
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Provided below are standard protocols that you may find useful for product applications.
This gene is a member of the ADAR (adenosine deaminaseacting on RNA) family. Using site-specific adenosine modification,proteins encoded by these genes participate in the pre-mRNA editingof nuclear transcripts. The protein encoded by this gene,tRNA-specific adenosine deaminase 1, is responsible for thedeamination of adenosine 37 to inosine in eukaryotic tRNA.Alternatively spliced transcript variants have been described.
Dastani, Z., et al. Eur. J. Hum. Genet. 18(3):342-347(2010)Maas, S., et al. Proc. Natl. Acad. Sci. U.S.A. 96(16):8895-8900(1999)
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