|Other Names||Iron-sulfur protein NUBPL, IND1 homolog, Nucleotide-binding protein-like, huInd1, NUBPL, C14orf127|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Required for the assembly of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I). May deliver of one or more Fe-S clusters to complex I subunits.|
|Tissue Location||Highest expression in liver and kidney. expressed at significant levels in small intestine and brain (at protein level).|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Respiratory complex I (NADH:ubiquinone oxidoreductase EC220.127.116.11) is a large mitochondrial inner membrane enzyme consistingof 45 subunits and 8 iron-sulfur (Fe/S) clusters. NUBPL, or IND1,is an Fe/ S protein that plays a critical role in the assembly ofrespiratory complex I, likely by transferring Fe/S into theFe/S-containing complex I subunits (Sheftel et al., 2009 [PubMed19752196]).
Calvo, S.E., et al. Nat. Genet. 42(10):851-858(2010)Sheftel, A.D., et al. Mol. Cell. Biol. 29(22):6059-6073(2009)Volpi, S., et al. Mol. Psychiatry 14(11):1024-1031(2009)Baranzini, S.E., et al. Hum. Mol. Genet. 18(4):767-778(2009)Lamesch, P., et al. Genomics 89(3):307-315(2007)
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.