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GPR62 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9BZJ7 |
|---|---|
| Clone Names | 110811090 |
| Gene ID | 118442 |
|---|---|
| Other Names | Probable G-protein coupled receptor 62, G-protein coupled receptor GPCR8, hGPCR8, G-protein coupled receptor KPG_005, GPR62 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | GPR62 |
|---|---|
| Function | Orphan G-protein coupled receptor. Constitutively activates the G(q/11)/inositol phosphate and the G(s)-alpha/cAMP signaling pathways (PubMed:28827538). Has spontaneous activity for beta-arrestin recruitment (PubMed:28827538). Shows a reciprocal modulation of signaling functions with the melatonin receptor MTNR1B most likely through receptor heteromerization (PubMed:28827538). |
| Cellular Location | Cell membrane; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein. Note=Colocalizes with ARRB2 in the endosome (PubMed:28827538). |
| Tissue Location | Expressed in brain; detected in the basal forebrain, frontal cortex, caudate, putamen, thalamus and hippocampus |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
G protein-coupled receptors (GPCRs, or GPRs) contain 7transmembrane domains and transduce extracellular signals throughheterotrimeric G proteins.
References
Takeda, S., et al. FEBS Lett. 520 (1-3), 97-101 (2002) :Lee, D.K., et al. Brain Res. Mol. Brain Res. 86 (1-2), 13-22 (2001) :
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