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ARSA Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession O43681
Clone Names 90429032
Peptide ID 90429032
Additional Information
Gene ID 439
Other Names ATPase ASNA1 {ECO:0000255|HAMAP-Rule:MF_03112}, 36-- {ECO:0000255|HAMAP-Rule:MF_03112}, Arsenical pump-driving ATPase {ECO:0000255|HAMAP-Rule:MF_03112}, Arsenite-stimulated ATPase {ECO:0000255|HAMAP-Rule:MF_03112}, Transmembrane domain recognition complex 40 kDa ATPase subunit, hARSA-I, hASNA-I, ASNA1 {ECO:0000255|HAMAP-Rule:MF_03112}, ARSA, TRC40
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name ASNA1 {ECO:0000255|HAMAP-Rule:MF_03112}
Synonyms ARSA, TRC40
Function ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail- anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting (By similarity). May be involved in insulin signaling.
Cellular Location Cytoplasm. Endoplasmic reticulum. Nucleus, nucleolus
Tissue Location Expressed in the epithelial cells of the liver, kidney, and stomach wall, in the adrenal medulla, in the islet cells of the pancreas, in the red pulp of the spleen, and in cardiac and skeletal muscle.
Research Areas
Citations (0)

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ASNA1 is the human homolog of the bacterial arsA gene. InE. coli, ArsA ATPase is the catalytic component of a multisubunitoxyanion pump that is responsible for resistance to arsenicals andantimonials.


Favaloro, V., et al. J. Cell. Sci. 123 (PT 9), 1522-1530 (2010) :Hemmingsson, O., et al. Oncol. Rep. 22(4):869-875(2009)Rabu, C., et al. J. Biol. Chem. 283(41):27504-27513(2008)Stefanovic, S., et al. Cell 128(6):1147-1159(2007)Kao, G., et al. Cell 128(3):577-587(2007)

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$ 80.00
Cat# BP18128b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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