|Other Names||Solute carrier family 15 member 4, Peptide transporter 4, Peptide/histidine transporter 1, hPHT1, SLC15A4, PHT1, PTR4|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Proton oligopeptide cotransporter. Transports free histidine and certain di- and tripeptides.|
|Cellular Location||Membrane; Multi-pass membrane protein|
|Tissue Location||Highly expressed in skeletal muscle. Moderately expressed in kidney, liver, and heart. Weakly expressed in colon and brain. Expressed in low levels throughout the gastrointestinal tract and in Caco-2 cells. Expressed in retinal fragment epithelium (RPE) and neural retina. Expressed in small intestine, stomach, duodenum, jejunum, ileum and colon|
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Provided below are standard protocols that you may find useful for product applications.
Proton oligopeptide cotransporter. Transports free histidine and certain di-and tripeptides.
He, C.F., et al. Lupus 19(10):1181-1186(2010)Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Han, J.W., et al. Nat. Genet. 41(11):1234-1237(2009)Takeuchi, F., et al. J. Hum. Genet. 53(4):314-324(2008)Bhardwaj, R.K., et al. Eur J Pharm Sci 27(5):533-542(2006)
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