|Other Names||Extracellular glycoprotein lacritin, LACRT|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Modulates secretion by lacrimal acinar cells.|
|Tissue Location||Expressed in secretory granules of many acinar cells in lacrimal gland and in scattered acinar cells of salivary glands|
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The protein encoded by this gene is highly expressed inthe lacrimal glands and localized primarily to secretory granulesand secretory fluid. It augments lacrimal acinar cell secretion,promotes ductal cell proliferation, and stimulates signalingthrough tyrosine phosphorylation and release of calcium. [providedby RefSeq].
Morimoto-Tochigi, A., et al. Invest. Ophthalmol. Vis. Sci. 51(9):4395-4406(2010)Nichols, J.J., et al. Cornea 28(10):1109-1117(2009)McKown, R.L., et al. Exp. Eye Res. 88(5):848-858(2009)Lei, Z., et al. J. Proteome Res. 8(4):1992-2003(2009)Green-Church, K.B., et al. Mol. Vis. 14, 291-297 (2008) :
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