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UGT2B7 Antibody (N-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession P16662
Clone Names 100311160
Peptide ID 100311160
Additional Information
Gene ID 7364
Other Names UDP-glucuronosyltransferase 2B7, UDPGT 2B7, 4-catechol estrogen-specific UDPGT, UDP-glucuronosyltransferase 2B9, UDPGT 2B9, UDPGTh-2, UGT2B7, UGTB2B9
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name UGT2B7
Synonyms UGTB2B9
Function UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds.
Cellular Location Microsome membrane; Single- pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein
Research Areas
Citations (0)

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Background

The UGTs (EC 2.4.1.17) serve a major role in theconjugation and subsequent elimination of potentially toxicxenobiotics and endogenous compounds. UGT2B7 has unique specificityfor 3,4-catechol estrogens and estriol, suggesting that it may playan important role in regulating the level and activity of thesepotent estrogen metabolites. Its subcellular location is themicrosome.

References

Joy, M.S., et al. Eur. J. Clin. Pharmacol. 66(11):1119-1130(2010)Canzian, F., et al. Hum. Mol. Genet. 19(19):3873-3884(2010)Hu, M., et al. Pharmacogenet. Genomics 20(10):634-637(2010)Woillard, J.B., et al. Br J Clin Pharmacol 69(6):675-683(2010)Hwang, M.S., et al. Drug Metab. Pharmacokinet. 25(4):398-402(2010)

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$ 80.00
Cat# BP18210a
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