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DRAM Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q8N682
Clone Names 70319101
Additional Information
Gene ID 55332
Other Names DNA damage-regulated autophagy modulator protein 1, Damage-regulated autophagy modulator, DRAM1, DRAM
Target/Specificity The synthetic peptide sequence used to generate the antibody AP1825c was selected from the C-term region of human DRAM. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name DRAM1
Synonyms DRAM
Function Lysosomal modulator of autophagy that plays a central role in p53/TP53-mediated apoptosis. Not involved in p73/TP73- mediated autophagy.
Cellular Location Lysosome membrane; Multi-pass membrane protein
Research Areas
Citations (0)

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DRAM is regulated as part of the p53 tumor suppressor pathway. It is a lysosomal membrane protein that is required for the induction of autophagy by the pathway. Decreased transcriptional expression of this protein is associated with various tumors.


Kerley-Hamilton,J.S., Biochim. Biophys. Acta 1769 (4), 209-219 (2007)Crighton,D., Autophagy 3 (1), 72-74 (2007)Crighton,D., Cell 126 (1), 121-134 (2006)Green,D.R., Cell 126 (1), 30-32 (2006)

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$ 80.00
Cat# BP1825c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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