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POU2F1 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P14859
Clone Names 81028120
Peptide ID 81028120
Additional Information
Gene ID 5451
Other Names POU domain, class 2, transcription factor 1, NF-A1, Octamer-binding protein 1, Oct-1, Octamer-binding transcription factor 1, OTF-1, POU2F1, OCT1, OTF1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name POU2F1
Synonyms OCT1, OTF1
Function Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. Modulates transcription transactivation by NR3C1, AR and PGR (By similarity). In case of human herpes simplex virus (HSV) infection, POU2F1 forms a multiprotein-DNA complex with the viral transactivator protein VP16 and HCFC1 thereby enabling the transcription of the viral immediate early genes.
Cellular Location Nucleus.
Tissue Location Ubiquitous. Isoform 2 is lymphocyte-specific.
Research Areas
Citations (0)

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The OCT1 transcription factor was among the firstidentified members of the POU transcription factor family(summarized by Sturm et al., 1993 [PubMed 8314572]). Members ofthis family contain the POU domain, a 160-amino acid regionnecessary for DNA binding to the octameric sequenceATGCAAAT.


Vuzman, D., et al. Biophys. J. 99(4):1202-1211(2010)Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Davila, S., et al. Genes Immun. 11(3):232-238(2010)Laurent, B., et al. Blood 115(3):687-695(2010)Becker, M.L., et al. Pharmacogenet. Genomics 20(1):38-44(2010)

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$ 80.00
Cat# BP18315a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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