|Other Names||Osteopetrosis-associated transmembrane protein 1, Chloride channel 7 beta subunit, OSTM1, GL|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Required for osteoclast and melanocyte maturation and function.|
|Cellular Location||Lysosome membrane; Single-pass type I membrane protein. Note=Requires CLCN7 to travel to lysosomes|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
This gene encodes a protein that may be involved in thedegradation of G proteins via the ubiquitin-dependent proteasomepathway. The encoded protein binds to members of subfamily A of theregulator of the G-protein signaling (RGS) family through anN-terminal leucine-rich region. This protein also has a centralRING finger-like domain and E3 ubiquitin ligase activity. Thisprotein is highly conserved from flies to humans. Defects in thisgene may cause the autosomal recessive, infantile malignant form ofosteopetrosis.
Yerges, L.M., et al. J. Bone Miner. Res. 24(12):2039-2049(2009)Mazzolari, E., et al. Am. J. Hematol. 84(8):473-479(2009)Vieira, A.R., et al. Genet. Med. 10(9):668-674(2008)Feigin, M.E., et al. Cell. Signal. 20(5):949-957(2008)Maranda, B., et al. J. Bone Miner. Res. 23(2):296-300(2008)
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.