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OSTM1 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q86WC4 |
|---|---|
| Clone Names | 100324052 |
| Gene ID | 28962 |
|---|---|
| Other Names | Osteopetrosis-associated transmembrane protein 1, Chloride channel 7 beta subunit, OSTM1, GL |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | OSTM1 |
|---|---|
| Synonyms | GL |
| Function | Required for osteoclast and melanocyte maturation and function. |
| Cellular Location | Lysosome membrane; Single-pass type I membrane protein Note=Requires CLCN7 to travel to lysosomes |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a protein that may be involved in thedegradation of G proteins via the ubiquitin-dependent proteasomepathway. The encoded protein binds to members of subfamily A of theregulator of the G-protein signaling (RGS) family through anN-terminal leucine-rich region. This protein also has a centralRING finger-like domain and E3 ubiquitin ligase activity. Thisprotein is highly conserved from flies to humans. Defects in thisgene may cause the autosomal recessive, infantile malignant form ofosteopetrosis.
References
Yerges, L.M., et al. J. Bone Miner. Res. 24(12):2039-2049(2009)Mazzolari, E., et al. Am. J. Hematol. 84(8):473-479(2009)Vieira, A.R., et al. Genet. Med. 10(9):668-674(2008)Feigin, M.E., et al. Cell. Signal. 20(5):949-957(2008)Maranda, B., et al. J. Bone Miner. Res. 23(2):296-300(2008)
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