|Other Names||Xenotropic and polytropic retrovirus receptor 1, Protein SYG1 homolog, Xenotropic and polytropic murine leukemia virus receptor X3, X-receptor, XPR1, SYG1, XR|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Plays a role in phosphate homeostasis. Mediates phosphate export from the cell (PubMed:23791524, PubMed:25938945). Binds inositol hexakisphosphate (Ins6P) and similar inositol polyphosphates, such as 5-diphospho-inositol pentakisphosphate (5- InsP7); these are important intracellular signaling molecules (PubMed:27080106).|
|Cellular Location||Cell membrane; Multi-pass membrane protein|
|Tissue Location||Widely expressed. Detected in spleen, lymph node, thymus, leukocytes, bone marrow, heart, kidney, pancreas and skeletal muscle.|
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Provided below are standard protocols that you may find useful for product applications.
XPR1 may function in G-protein coupled signal transduction (By similarity). Potential receptor for xenotropic and polytropic murine leukemia retroviruses.
Bhosle, S., et al. J. Virol. 84(13):6288-6296(2010)Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Battini, J.L., et al. Proc. Natl. Acad. Sci. U.S.A. 96(4):1385-1390(1999)Tailor, C.S., et al. Proc. Natl. Acad. Sci. U.S.A. 96(3):927-932(1999)Yang, Y.L., et al. Nat. Genet. 21(2):216-219(1999)
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