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MEOX2 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P50222
Clone Names 100430156
Peptide ID 100430156
Additional Information
Gene ID 4223
Other Names Homeobox protein MOX-2, Growth arrest-specific homeobox, Mesenchyme homeobox 2, MEOX2, GAX, MOX2
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name MEOX2
Synonyms GAX, MOX2
Function Mesodermal transcription factor that plays a key role in somitogenesis and is required for sclerotome development (By similarity). Activates expression of CDKN1A and CDKN2A in endothelial cells, acting as a regulator of vascular cell proliferation. While it activates CDKN1A in a DNA-dependent manner, it activates CDKN2A in a DNA-independent manner (PubMed:22206000). May have a regulatory role when quiescent vascular smooth muscle cells reenter the cell cycle.
Cellular Location Nucleus. Nucleus speckle {ECO:0000255|PROSITE-ProRule:PRU00108, ECO:0000269|PubMed:19266028}
Tissue Location Embryo and placenta.
Research Areas
Citations (0)

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This gene encodes a member of a subfamily ofnon-clustered, diverged, antennapedia-like homeobox-containinggenes. The encoded protein may play a role in the regulation ofvertebrate limb myogenesis. Mutations in the related mouse proteinmay be associated with craniofacial and/or skeletal abnormalities,in addition to neurovascular dysfunction observed in Alzheimer'sdisease.


Rose, J. Phd, et al. Mol. Med. (2010) In press :Ohshima, J., et al. Genes Chromosomes Cancer 48(12):1037-1050(2009)Irelan, J.T., et al. PLoS ONE 4 (4), E5067 (2009) :Chen, Y., et al. Blood 111(3):1217-1226(2008)Valcourt, U., et al. Mol Oncol 1(1):55-71(2007)

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$ 80.00
Cat# BP18398c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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