|Other Names||Guanylate-binding protein 3, GTP-binding protein 3, GBP-3, Guanine nucleotide-binding protein 3, GBP3|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Exhibits antiviral activity against influenza virus.|
|Cellular Location||Cytoplasm. Cytoplasm, perinuclear region. Golgi apparatus membrane Note=Heterodimers with GBP1, GBP2 and GBP5 localize in the compartment of the prenylated GBPs: with GBP1 in a vesicle-like compartment, with GBP2, around the nucleus and with GBP-5, at the Golgi aparatus.|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the guanylate-bindingprotein (GBP) family. GBPs specifically bind guanine nucleotides(GMP, GDP, and GTP) and contain two of the three consensus motifsfound in typical GTP-binding proteins. The encoded proteininteracts with a member of the germinal center kinase family.
Davila, S., et al. Genes Immun. 11(3):232-238(2010)Luan, Z., et al. FEBS Lett. 530 (1-3), 233-238 (2002) :Strehlow, I., et al. Gene 144(2):295-299(1994)
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