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RHOT1 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q8IXI2 |
|---|---|
| Clone Names | 110819072 |
| Gene ID | 55288 |
|---|---|
| Other Names | Mitochondrial Rho GTPase 1, MIRO-1, hMiro-1, 365-, Rac-GTP-binding protein-like protein, Ras homolog gene family member T1, RHOT1, ARHT1 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | RHOT1 |
|---|---|
| Synonyms | ARHT1 |
| Function | Mitochondrial GTPase involved in mitochondrial trafficking (PubMed:12482879, PubMed:16630562, PubMed:22396657). Probably involved in control of anterograde transport of mitochondria and their subcellular distribution (PubMed:12482879, PubMed:16630562, PubMed:22396657). Promotes mitochondrial fission during high calcium conditions (PubMed:27716788). |
| Cellular Location | Mitochondrion outer membrane; Single-pass type IV membrane protein. Note=Colocalizes with MGARP and RHOT2 at the mitochondria |
| Tissue Location | Ubiquitously expressed. Expressed at high level in heart and skeletal muscle. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Mitochondrial GTPase involved in mitochondrial trafficking. Probably involved in control of anterograde transport of mitochondria and their subcellular distribution.
References
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :MacAskill, A.F., et al. Mol. Cell. Neurosci. 40(3):301-312(2009)Wang, X., et al. Cell 136(1):163-174(2009)Saotome, M., et al. Proc. Natl. Acad. Sci. U.S.A. 105(52):20728-20733(2008)Fransson, S., et al. Biochem. Biophys. Res. Commun. 344(2):500-510(2006)
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