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LDOC1L Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q6ICC9 |
|---|---|
| Clone Names | 110729125 |
| Gene ID | 84247 |
|---|---|
| Other Names | Protein LDOC1L, Leucine zipper protein down-regulated in cancer cells-like, Mammalian retrotransposon-derived protein 6, LDOC1L, MAR6, MART6 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | RTL6 (HGNC:13343) |
|---|
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Provided below are standard protocols that you may find useful for product applications.
Background
LDOC1 (Leucine zipper protein downregulated in cancer cells) is a 146 amino acid nuclear protein that contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is downregulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kB (NF-kB). The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers. LDOC1L (Leucine zipper protein down-regulated in cancer cells-like), also known as MART6 (Mammalian retrotransposon-derived protein 6), is a 239 amino acid protein that belongs to the LDOC1 family.
References
Brandt, J., et al. Gene 345(1):101-111(2005)Brandt, J., et al. Cytogenet. Genome Res. 110 (1-4), 307-317 (2005) :Collins, J.E., et al. Genome Biol. 5 (10), R84 (2004) :
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