|Other Names||Group IIE secretory phospholipase A2, GIIE sPLA2, sPLA2-IIE, Phosphatidylcholine 2-acylhydrolase 2E, PLA2G2E|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||PA2 catalyzes the calcium-dependent hydrolysis of the 2- acyl groups in 3-sn-phosphoglycerides. Has a preference for arachidonic-containing phospholipids.|
|Tissue Location||Restricted to the brain, heart, lung, and placenta|
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Provided below are standard protocols that you may find useful for product applications.
PA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides. Has a preference for arachidonic-containing phospholipids.
McGovern, D.P., et al. Nat. Genet. 42(4):332-337(2010)Segat, L., et al. Vaccine 28(10):2201-2206(2010)Barrett, J.C., et al. Nat. Genet. 41(12):1330-1334(2009)Silverberg, M.S., et al. Nat. Genet. 41(2):216-220(2009)Murakami, M., et al. Biochem. Biophys. Res. Commun. 292(3):689-696(2002)
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