LAX1 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q8IWV1 |
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Clone Names | 110717095 |
Gene ID | 54900 |
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Other Names | Lymphocyte transmembrane adapter 1, Linker for activation of X cells, Membrane-associated adapter protein LAX, LAX1, LAX |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | LAX1 |
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Synonyms | LAX |
Function | Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells and BCR (B-cell antigen receptor)-mediated signaling in B-cells. |
Cellular Location | Cell membrane; Single-pass type III membrane protein |
Tissue Location | Expressed in spleen, thymus, and peripheral blood leukocytes. Expressed in several B-, T-, NK and monocyte cell lines |
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Provided below are standard protocols that you may find useful for product applications.
Background
LAX1 negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells and BCR (B-cell antigen receptor)-mediated signaling in B-cells.
References
Ehret, G.B., et al. Eur. J. Hum. Genet. 17(12):1650-1657(2009)Shapiro, M.J., et al. J. Immunol. 181(10):7055-7061(2008)Zhu, M., et al. J. Immunol. 174(9):5612-5619(2005)Zhu, M., et al. J. Biol. Chem. 277(48):46151-46158(2002)
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