|Other Names||Calcium-responsive transcription factor, Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein, Calcium-response factor, CaRF, Testis development protein NYD-SP24, CARF, ALS2CR8|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Acts as a transcriptional activator that mediates the calcium- and neuron-selective induction of BDNF exon III transcription. Binds to the consensus calcium-response element CaRE1 5'-CTATTTCGAG-3' sequence.|
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Provided below are standard protocols that you may find useful for product applications.
ALS2CR8 may be a transcription factor (By similarity).
Cheung, C.T., et al. Mech. Ageing Dev. 130 (1-2), 18-23 (2009) :Hillier, L.W., et al. Nature 434(7034):724-731(2005)Hasan, M.K., et al. J. Biol. Chem. 277(40):37765-37770(2002)Tao, X., et al. Neuron 33(3):383-395(2002)Hadano, S., et al. Nat. Genet. 29(2):166-173(2001)
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