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Mouse Dcdc2 Antibody (C-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q5DU00
Clone Names 110819125
Peptide ID 110819125
Additional Information
Gene ID 195208
Other Names Doublecortin domain-containing protein 2, Dcdc2, Dcdc2a, Kiaa1154
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name Dcdc2
Synonyms Dcdc2a, Kiaa1154
Function Protein that plays a role in the inhibition of canonical Wnt signaling pathway (By similarity). May be involved in neuronal migration during development of the cerebral neocortex (By similarity). Involved in the control of ciliogenesis and ciliary length (By similarity).
Cellular Location Cell projection, cilium {ECO:0000250|UniProtKB:Q9UHG0}. Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000250|UniProtKB:Q9UHG0}. Cell projection, kinocilium {ECO:0000250|UniProtKB:D3ZR10}. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:D3ZR10}. Note=Localizes to the ciliary axoneme and to mitotic spindle fibers in a cell-cycle-dependent manner. {ECO:0000250|UniProtKB:Q9UHG0}
Tissue Location Expressed in hair cells of the inner ear.
Research Areas
Citations (0)

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Background

This gene encodes a member of the doublecortin family. Theprotein encoded by this gene contains two doublecortin domains. Thedoublecortin domain has been demonstrated to bind tubulin andenhance microtubule polymerization. Alternatively splicedtranscript variants encoding distinct isoforms have been found forthis gene.

References

Dijkmans, T.F., et al. Cent Nerv Syst Agents Med Chem 10(1):32-46(2010)Coquelle, F.M., et al. Cell Cycle 5(9):976-983(2006)Reiner, O., et al. BMC Genomics 7, 188 (2006) :

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$ 80.00
Cat# BP18686b
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