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GSC Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P56915 |
|---|---|
| Clone Names | 110717067 |
| Gene ID | 145258 |
|---|---|
| Other Names | Homeobox protein goosecoid, GSC |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | GSC |
|---|---|
| Function | Regulates chordin (CHRD). May play a role in spatial programing within discrete embryonic fields or lineage compartments during organogenesis. In concert with NKX3-2, plays a role in defining the structural components of the middle ear; required for the development of the entire tympanic ring (By similarity). Probably involved in the regulatory networks that define neural crest cell fate specification and determine mesoderm cell lineages in mammals. |
| Cellular Location | Nucleus. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of the bicoid subfamily of thepaired (PRD) homeobox family of proteins. The encoded protein actsas a transcription factor and may be autoregulatory. A similarprotein in mice plays a role in craniofacial and rib cagedevelopment during embryogenesis.
References
Zhang, Q., et al. Plast. Reconstr. Surg. 125(3):979-987(2010)Paterson, A.D., et al. Diabetes 59(2):539-549(2010)Zhang, Q.G., et al. Plast. Reconstr. Surg. 124(4):1157-1164(2009)Schlade-Bartusiak, K., et al. Am. J. Med. Genet. A 146A (1), 117-123 (2008) :Hartwell, K.A., et al. Proc. Natl. Acad. Sci. U.S.A. 103(50):18969-18974(2006)
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