|Other Names||Leucine-rich repeat transmembrane neuronal protein 2, Leucine-rich repeat neuronal 2 protein, LRRTM2, KIAA0416, LRRN2|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Involved in the development and maintenance of excitatory synapse in the vertebrate nervous system. Regulates surface expression of AMPA receptors and instructs the development of functional glutamate release sites. Acts as a ligand for the presynaptic receptors NRXN1-A and NRXN1-B (By similarity).|
|Cellular Location||Cell membrane; Single-pass type I membrane protein. Cell junction, synapse, postsynaptic cell membrane; Single-pass type I membrane protein Note=Localized to excitatory synapses.|
|Tissue Location||Expressed in neuronal tissues.|
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Provided below are standard protocols that you may find useful for product applications.
LRRTM2 may play a role in the development and maintenance of the vertebrate nervous system.
Graubert, T.A., et al. PLoS ONE 4 (2), E4583 (2009) :Lauren, J., et al. Genomics 81(4):411-421(2003)
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