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NCAPH Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q15003
Clone Names 100603043
Peptide ID 100603043
Additional Information
Gene ID 23397
Other Names Condensin complex subunit 2, Barren homolog protein 1, Chromosome-associated protein H, hCAP-H, Non-SMC condensin I complex subunit H, XCAP-H homolog, NCAPH, BRRN, BRRN1, CAPH, KIAA0074
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms BRRN, BRRN1, CAPH, KIAA0074
Function Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.
Cellular Location Nucleus. Cytoplasm. Chromosome. Note=In interphase cells, the majority of the condensin complex is found in the cytoplasm, while a minority of the complex is associated with chromatin. A subpopulation of the complex however remains associated with chromosome foci in interphase cells. During mitosis, most of the condensin complex is associated with the chromatin. At the onset of prophase, the regulatory subunits of the complex are phosphorylated by CDK1, leading to condensin's association with chromosome arms and to chromosome condensation. Dissociation from chromosomes is observed in late telophase
Tissue Location Widely expressed at low level. Expressed in proliferating cells.
Research Areas
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This gene encodes a member of the barr gene family and aregulatory subunit of the condensin complex. This complex isrequired for the conversion of interphase chromatin into condensedchromosomes. The protein encoded by this gene is associated withmitotic chromosomes, except during the early phase of chromosomecondensation. During interphase, the protein has a distinctpunctate nucleolar localization.


Olsen, J.V., et al. Cell 127(3):635-648(2006)Beausoleil, S.A., et al. Nat. Biotechnol. 24(10):1285-1292(2006)Nousiainen, M., et al. Proc. Natl. Acad. Sci. U.S.A. 103(14):5391-5396(2006)Nousiainen, M., et al. Proc. Natl. Acad. Sci. U.S.A. 103(14):5391-5396(2006)Heale, J.T., et al. Mol. Cell 21(6):837-848(2006)

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$ 80.00
Cat# BP18809c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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