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PHLDA1 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q8WV24 |
|---|---|
| Clone Names | 110901048 |
| Gene ID | 22822 |
|---|---|
| Other Names | Pleckstrin homology-like domain family A member 1, Apoptosis-associated nuclear protein, Proline- and glutamine-rich protein, PQ-rich protein, PQR protein, Proline- and histidine-rich protein, T-cell death-associated gene 51 protein, PHLDA1, PHRIP, TDAG51 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | PHLDA1 |
|---|---|
| Synonyms | PHRIP, TDAG51 |
| Function | Seems to be involved in regulation of apoptosis. May be involved in detachment-mediated programmed cell death. May mediate apoptosis during neuronal development. May be involved in regulation of anti-apoptotic effects of IGF1. May be involved in translational regulation. |
| Cellular Location | Cytoplasm. Cytoplasmic vesicle. Nucleus, nucleolus. Note=Colocalizes with intracellular vesicles. |
| Tissue Location | Widely expressed with highest levels in pancreas. Strongly expressed by benign melanocytic nevi, and progressively reduced expressed in primary and metastatic melanomas (at protein level). |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes an evolutionarily conservedproline-histidine rich nuclear protein. The encoded protein mayplay an important role in the anti-apoptotic effects ofinsulin-like growth factor-1.
References
Venkatesan, K., et al. Nat. Methods 6(1):83-90(2009)Marchiori, A.C., et al. Braz. J. Med. Biol. Res. 41(7):579-582(2008)Nagai, M.A., et al. Breast Cancer Res. Treat. 106(1):49-56(2007)Xi, Z.Q., et al. Neurosci. Lett. 425(1):53-58(2007)Meier-Noorden, M., et al. Gene 338(2):197-207(2004)
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