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RAB22A Antibody (C-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q9UL26
Clone Names 110901089
Peptide ID 110901089
Additional Information
Gene ID 57403
Other Names Ras-related protein Rab-22A, Rab-22, RAB22A, RAB22
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name RAB22A
Synonyms RAB22
Function Plays a role in endocytosis and intracellular protein transport. Mediates trafficking of TF from early endosomes to recycling endosomes. Required for NGF-mediated endocytosis of NTRK1, and subsequent neurite outgrowth. Binds GTP and GDP and has low GTPase activity. Alternates between a GTP-bound active form and a GDP-bound inactive form.
Cellular Location Endosome membrane {ECO:0000250|UniProtKB:P51154}; Lipid-anchor. Cell membrane {ECO:0000250|UniProtKB:P51154}; Lipid-anchor. Early endosome. Late endosome {ECO:0000250|UniProtKB:P51154}. Cell projection, ruffle. Cytoplasmic vesicle. Cytoplasmic vesicle, phagosome. Cytoplasmic vesicle, phagosome membrane; Lipid-anchor; Cytoplasmic side. Note=Recruited to phagosomes containing S.aureus or M.tuberculosis.
Research Areas
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Background

The protein encoded by this gene is a member of the RABfamily of small GTPases. The GTP-bound form of the encoded proteinhas been shown to interact with early-endosomal antigen 1, and maybe involved in the trafficking of and interaction between endosomalcompartments.

References

Zhu, H., et al. Mol. Biol. Cell 20(22):4720-4729(2009)Magadan, J.G., et al. Mol. Cell. Biol. 26(7):2595-2614(2006)Mesa, R., et al. Exp. Cell Res. 304(2):339-353(2005)Barrios-Rodiles, M., et al. Science 307(5715):1621-1625(2005)Weigert, R., et al. Mol. Biol. Cell 15(8):3758-3770(2004)

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$ 80.00
Cat# BP18867b
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