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RAB22A Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9UL26 |
|---|---|
| Clone Names | 110901089 |
| Gene ID | 57403 |
|---|---|
| Other Names | Ras-related protein Rab-22A, Rab-22, RAB22A, RAB22 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | RAB22A |
|---|---|
| Synonyms | RAB22 |
| Function | Plays a role in endocytosis and intracellular protein transport. Mediates trafficking of TF from early endosomes to recycling endosomes (PubMed:16537905). Required for NGF-mediated endocytosis of NTRK1, and subsequent neurite outgrowth (PubMed:21849477). Binds GTP and GDP and has low GTPase activity. Alternates between a GTP-bound active form and a GDP-bound inactive form (PubMed:16537905). |
| Cellular Location | Endosome membrane {ECO:0000250|UniProtKB:P51154}; Lipid-anchor. Cell membrane {ECO:0000250|UniProtKB:P51154}; Lipid-anchor. Early endosome. Late endosome {ECO:0000250|UniProtKB:P51154}. Cell projection, ruffle. Cytoplasmic vesicle. Cytoplasmic vesicle, phagosome. Cytoplasmic vesicle, phagosome membrane; Lipid-anchor; Cytoplasmic side. Note=Recruited to phagosomes containing S.aureus or M.tuberculosis. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene is a member of the RABfamily of small GTPases. The GTP-bound form of the encoded proteinhas been shown to interact with early-endosomal antigen 1, and maybe involved in the trafficking of and interaction between endosomalcompartments.
References
Zhu, H., et al. Mol. Biol. Cell 20(22):4720-4729(2009)Magadan, J.G., et al. Mol. Cell. Biol. 26(7):2595-2614(2006)Mesa, R., et al. Exp. Cell Res. 304(2):339-353(2005)Barrios-Rodiles, M., et al. Science 307(5715):1621-1625(2005)Weigert, R., et al. Mol. Biol. Cell 15(8):3758-3770(2004)
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