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G2E3 Antibody (Center) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q7L622
Clone Names 110826137
Peptide ID 110826137
Additional Information
Gene ID 55632
Other Names G2/M phase-specific E3 ubiquitin-protein ligase, 632-, G2E3, KIAA1333
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name G2E3
Synonyms KIAA1333
Function E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Essential in early embryonic development to prevent apoptotic death.
Cellular Location Nucleus, nucleolus. Cytoplasm. Note=Shuttles between the nucleus and the cytoplasm. In the nucleus, delocalizes from the nucleolus to the nucleoplasm in response to DNA damage
Tissue Location Predominantly expressed in brain, liver, kidney, testes and ovary.
Research Areas
Citations (0)

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Background

E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Essential in early embryonic development to prevent apoptotic death.

References

Brooks, W.S., et al. J. Biol. Chem. 283(32):22304-22315(2008)Brooks, W.S., et al. Exp. Cell Res. 313(4):665-676(2007)Lehner, B., et al. Genomics 83(1):153-167(2004)Crawford, D.F., et al. J. Biol. Chem. 276(40):37166-37177(2001)

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$ 80.00
Cat# BP18914c
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