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ITPA Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q9BY32
Clone Names 100311246
Peptide ID 100311246
Additional Information
Gene ID 3704
Other Names Inosine triphosphate pyrophosphatase {ECO:0000255|HAMAP-Rule:MF_03148}, ITPase {ECO:0000255|HAMAP-Rule:MF_03148}, Inosine triphosphatase {ECO:0000255|HAMAP-Rule:MF_03148}, 36119 {ECO:0000255|HAMAP-Rule:MF_03148}, Non-canonical purine NTP pyrophosphatase {ECO:0000255|HAMAP-Rule:MF_03148}, Non-standard purine NTP pyrophosphatase {ECO:0000255|HAMAP-Rule:MF_03148}, Nucleoside-triphosphate diphosphatase {ECO:0000255|HAMAP-Rule:MF_03148}, Nucleoside-triphosphate pyrophosphatase {ECO:0000255|HAMAP-Rule:MF_03148}, NTPase {ECO:0000255|HAMAP-Rule:MF_03148}, Putative oncogene protein hlc14-06-p, ITPA {ECO:0000255|HAMAP-Rule:MF_03148}, C20orf37
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name ITPA {ECO:0000255|HAMAP-Rule:MF_03148}
Synonyms C20orf37
Function Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.
Cellular Location Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03148, ECO:0000269|PubMed:11278832}
Tissue Location Ubiquitous. Highly expressed in heart, liver, sex glands, thyroid and adrenal gland
Research Areas
Citations (0)

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The protein encoded by this gene hydrolyzes inosinetriphosphate and deoxyinosine triphosphate to the monophosphatenucleotide and diphosphate. The encoded protein, which is a memberof the HAM1 NTPase protein family, is found in the cytoplasm andacts as a homodimer. Defects in the encoded protein can result ininosine triphosphate pyrophosphorylase deficiency. Two transcriptvariants encoding two different isoforms have been found for thisgene. Also, at least two other transcript variants have beenidentified which are probably regulatory rather thanprotein-coding.


Kim, J.H., et al. J. Clin. Gastroenterol. 44 (10), E242-E248 (2010) :Ochi, H., et al. Gastroenterology 139(4):1190-1197(2010)Thompson, A.J., et al. Gastroenterology 139(4):1181-1189(2010)Ban, H., et al. J. Gastroenterol. 45(10):1014-1021(2010)Fellay, J., et al. Nature 464(7287):405-408(2010)

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$ 80.00
Cat# BP18963b
Availability: In Stock
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