Register or Login
  • All
  • Uniprot Id
  • Catalog #
  • Peptide Sequence
>   home   >   Products   >   Peptides   >   Blocking Peptides   >   DMP1 Antibody (N-term) Blocking Peptide   

DMP1 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q13316
Clone Names 100311261
Peptide ID 100311261
Additional Information
Gene ID 1758
Other Names Dentin matrix acidic phosphoprotein 1, DMP-1, Dentin matrix protein 1, DMP1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name DMP1
Function May have a dual function during osteoblast differentiation. In the nucleus of undifferentiated osteoblasts, unphosphorylated form acts as a transcriptional component for activation of osteoblast-specific genes like osteocalcin. During the osteoblast to osteocyte transition phase it is phosphorylated and exported into the extracellular matrix, where it regulates nucleation of hydroxyapatite.
Cellular Location Nucleus. Cytoplasm. Secreted, extracellular space, extracellular matrix. Note=In proliferating preosteoblasts it is nuclear, during early maturation stage is cytoplasmic and in mature osteoblast localizes in the mineralized matrix. Export from the nucleus of differentiating osteoblast is triggered by the release of calcium from intracellular stores followed by a massive influx of this pool of calcium into the nucleus
Tissue Location Expressed in tooth particularly in odontoblast, ameloblast and cementoblast
Research Areas
Citations (0)

Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.

Submit your citation using an Abgent antibody to, and receive a free "I Love Antibodies" mug.


Dentin matrix acidic phosphoprotein is an extracellularmatrix protein and a member of the small integrin binding ligandN-linked glycoprotein family. This protein, which is critical forproper mineralization of bone and dentin, is present in diversecells of bone and tooth tissues. The protein contains a largenumber of acidic domains, multiple phosphorylation sites, afunctional arg-gly-asp cell attachment sequence, and a DNA bindingdomain. In undifferentiated osteoblasts it is primarily a nuclearprotein that regulates the expression of osteoblast-specific genes.During osteoblast maturation the protein becomes phosphorylated andis exported to the extracellular matrix, where it orchestratesmineralized matrix formation. Mutations in the gene are known tocause autosomal recessive hypophosphatemia, a disease thatmanifests as rickets and osteomalacia. The gene structure isconserved in mammals. Two transcript variants encoding differentisoforms have been described for this gene.


Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Joslyn, G., et al. Alcohol. Clin. Exp. Res. 34(5):800-812(2010)Turan, S., et al. Bone 46(2):402-409(2010)Pereira, R.C., et al. Bone 45(6):1161-1168(2009)Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)

Abgent welcomes feedback from its customers.

If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.

If you have any additional inquiries please email technical services at

$ 80.00
Cat# BP18965a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
Request Quote Here

Ordering Information

United States
AlbaniaAustraliaAustriaBelgiumBosnia & HerzegovinaBrazilBulgariaCanadaChinaCroatiaCyprusCzech RepublicDenmarkEstoniaFinlandFranceGermanyGreeceHong KongHungaryIcelandIndiaIndonesiaIrelandIsraelItalyJapanKoreaLatviaLithuaniaLuxembourgMacedoniaMalaysiaMaltaNetherlandsNew ZealandNorwayPakistanPolandPortugalRomaniaSerbiaSingaporeSlovakiaSloveniaSouth AfricaSpainSwedenSwitzerlandTaiwanTurkeyUnited KingdomUnited StatesVietnamOthers
Abgent, Inc.
(888) 735-7227 / (858) 622-0099
(858) 622-0609

Shipping Information

Domestic orders (in stock items)
Shipped out the same day. Orders placed after 1 PM (PST) will ship out the next business day.
International orders
Contact your local distributors
Santa Cruz Alternative
Terms & Conditions