|Other Names||Non-secretory ribonuclease, Eosinophil-derived neurotoxin, RNase UpI-2, Ribonuclease 2, RNase 2, Ribonuclease US, RNASE2, EDN, RNS2|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||This is a non-secretory ribonuclease. It is a pyrimidine specific nuclease with a slight preference for U. Cytotoxin and helminthotoxin. Selectively chemotactic for dendritic cells. Possesses a wide variety of biological activities.|
|Cellular Location||Lysosome. Cytoplasmic granule. Note=Matrix of eosinophil's large specific granule|
|Tissue Location||Liver, lung, spleen, leukocytes and body fluids|
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Provided below are standard protocols that you may find useful for product applications.
This is a non-secretory ribonuclease. It is a pyrimidine specific nuclease with a slight preference for U. Cytotoxin and helminthotoxin. Selectively chemotactic for dendritic cells. Possesses a wide variety of biological activities.
McGovern, D.P., et al. Hum. Mol. Genet. 19(17):3468-3476(2010)Plager, D.A., et al. J. Immunol. 183(6):4013-4020(2009)Wang, H.Y., et al. J. Cell. Biochem. 106(2):317-326(2009)Ueki, M., et al. Cell Biochem. Funct. 26(6):718-722(2008)Parwez, Q., et al. J Negat Results Biomed 7, 9 (2008) :
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