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CDC42EP1 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q00587 |
|---|---|
| Clone Names | 100712282 |
| Gene ID | 11135 |
|---|---|
| Other Names | Cdc42 effector protein 1, Binder of Rho GTPases 5, Serum protein MSE55, CDC42EP1, BORG5, CEP1, MSE55 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | CDC42EP1 |
|---|---|
| Synonyms | BORG5, CEP1, MSE55 |
| Function | Probably involved in the organization of the actin cytoskeleton. Induced membrane extensions in fibroblasts. |
| Cellular Location | Endomembrane system; Peripheral membrane protein. Cytoplasm, cytoskeleton |
| Tissue Location | Endothelial and bone marrow stromal cells. |
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Provided below are standard protocols that you may find useful for product applications.
Background
CDC42 is a member of the Rho GTPase family that regulatesmultiple cellular activities, including actin polymerization. Theprotein encoded by this gene is a CDC42 binding protein thatmediates actin cytoskeleton reorganization at the plasma membrane.This protein is secreted and is primarily found in bone marrow.
References
Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)Olsen, J.V., et al. Cell 127(3):635-648(2006)Olsen, J.V., et al. Cell 127(3):635-648(2006)Zhang, J., et al. Mol. Biol. Cell 16(2):824-834(2005)Ballif, B.A., et al. Mol. Cell Proteomics 3(11):1093-1101(2004)
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