|Other Names||Cdc42 effector protein 1, Binder of Rho GTPases 5, Serum protein MSE55, CDC42EP1, BORG5, CEP1, MSE55|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Synonyms||BORG5, CEP1, MSE55|
|Function||Probably involved in the organization of the actin cytoskeleton. Induced membrane extensions in fibroblasts.|
|Cellular Location||Endomembrane system; Peripheral membrane protein. Cytoplasm, cytoskeleton|
|Tissue Location||Endothelial and bone marrow stromal cells.|
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Provided below are standard protocols that you may find useful for product applications.
CDC42 is a member of the Rho GTPase family that regulatesmultiple cellular activities, including actin polymerization. Theprotein encoded by this gene is a CDC42 binding protein thatmediates actin cytoskeleton reorganization at the plasma membrane.This protein is secreted and is primarily found in bone marrow.
Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)Olsen, J.V., et al. Cell 127(3):635-648(2006)Olsen, J.V., et al. Cell 127(3):635-648(2006)Zhang, J., et al. Mol. Biol. Cell 16(2):824-834(2005)Ballif, B.A., et al. Mol. Cell Proteomics 3(11):1093-1101(2004)
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