|Other Names||Transmembrane protein 8B, Nasopharyngeal carcinoma-associated gene 6 protein, Protein NAG-5, Protein NGX6, TMEM8B, C9orf127, NGX6|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||May function as a regulator of the EGFR pathway. Probable tumor suppressor which may function in cell growth, proliferation and adhesion.|
|Cellular Location||Isoform 2: Cell membrane; Multi-pass membrane protein. Cytoplasm. Nucleus. Mitochondrion. Endoplasmic reticulum. Note=Also detected in mitochondrion and endoplasmic reticulum (PubMed:17641538)|
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TMEM8B may function as a regulator of the EGFR pathway. Probable tumor suppressor which may function in cell growth, proliferation and adhesion.
Guo, Q., et al. Acta Biochim. Biophys. Sin. (Shanghai) 42(7):450-456(2010)Wang, L., et al. J. Histochem. Cytochem. 58(1):41-51(2010)Liu, M., et al. BMC Cancer 10, 160 (2010) :Peng, Y., et al. Acta Biochim. Biophys. Sin. (Shanghai) 41(6):504-514(2009)Peng, S.P., et al. Oncology 71 (3-4), 273-281 (2006) :
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