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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   GAS41 (YEATS4/NuBI-1) Antibody (N-term A31) Blocking peptide   

GAS41 (YEATS4/NuBI-1) Antibody (N-term A31) Blocking peptide

Synthetic peptide

Product Information
Primary Accession O95619
Clone Names 5081955
Peptide ID 5081955
Additional Information
Gene ID 8089
Other Names YEATS domain-containing protein 4, Glioma-amplified sequence 41, Gas41, NuMA-binding protein 1, NuBI-1, NuBI1, YEATS4, GAS41
Target/Specificity The synthetic peptide sequence used to generate the antibody AP1910a was selected from the N-term region of human NuBI-1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms GAS41
Function Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage.
Cellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00376, ECO:0000269|PubMed:10913114}
Tissue Location Expressed in brain, heart, kidney, liver, lung, pancreas, placenta and skeletal muscle
Research Areas
Citations (0)

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NuBI-1 is found in the nucleoli. It has high sequence homology to human MLLT1, and yeast and human MLLT3 proteins. Both MLLT1 and MLLT3 proteins belong to a class of transcription factors, indicating that the encoded protein might also represent a transcription factor. This protein is thought to be required for RNA transcription. The gene for this protein has been shown to be amplified in tumors.


Cai, Y., et al., J. Biol. Chem. 278(44):42733-42736 (2003).Lauffart, B., et al., Genomics 81(2):192-201 (2003).Zimmermann, K., et al., J. Biol. Chem. 277(21):18626-18631 (2002).Debernardi, S., et al., Blood 99(1):275-281 (2002).Munnia, A., et al., Oncogene 20(35):4853-4863 (2001).

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$ 80.00
Cat# BP1910a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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