|Other Names||Guanine nucleotide-binding protein subunit beta-4, Transducin beta chain 4, GNB4|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction.|
|Tissue Location||Strongly expressed in lung and placenta, whereas it is weakly expressed in brain and heart. Abundantly expressed in the axons and Schwann cells of peripheral nerves|
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Provided below are standard protocols that you may find useful for product applications.
Heterotrimeric guanine nucleotide-binding proteins (Gproteins), which integrate signals between receptors and effectorproteins, are composed of an alpha, a beta, and a gamma subunit.These subunits are encoded by families of related genes. This geneencodes a beta subunit. Beta subunits are important regulators ofalpha subunits, as well as of certain signal transduction receptorsand effectors.
Riemann, K., et al. Anticancer Res. 29(4):1271-1274(2009)Riemann, K., et al. Pharmacogenet. Genomics 18(11):999-1008(2008)Lamesch, P., et al. Genomics 89(3):307-315(2007)Rosskopf, D., et al. FEBS Lett. 544 (1-3), 27-32 (2003) :Jiang, G., et al. Am. J. Physiol. Endocrinol. Metab. 284 (4), E671-E678 (2003) :
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