|Other Names||Membrane transport protein XK, Kell complex 37 kDa component, Kx antigen, XK-related protein 1, XK, XKR1, XRG1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||May be involved in sodium-dependent transport of neutral amino acids or oligopeptides.|
|Cellular Location||Membrane; Multi-pass membrane protein|
|Tissue Location||High levels in skeletal muscle, heart, brain, and pancreas; low levels in placenta, lung, liver, and kidney|
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This locus controls the synthesis of the Kell blood group'precursor substance' (Kx). Mutations in this gene have beenassociated with McLeod syndrome, an X-linked, recessive disordercharacterized by abnormalities in the neuromuscular andhematopoietic systems. The encoded protein has structuralcharacteristics of prokaryotic and eukaryotic membrane transportproteins.
Miranda, M., et al. Mov. Disord. 22(9):1358-1361(2007)Claperon, A., et al. Brain Res. 1147, 12-24 (2007) :Walker, R.H., et al. Transfusion 47(2):299-305(2007)Olsen, J.V., et al. Cell 127(3):635-648(2006)Jung, H.H., et al. Transfusion 43(7):928-938(2003)
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