|Other Names||Signal-regulatory protein beta-2, SIRP-beta-2, Protein tyrosine phosphatase non-receptor type substrate 1-like 3, Protein tyrosine phosphatase non-receptor type substrate protein, SIRPB2, PTPN1L, PTPNS1L3|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Cellular Location||Membrane; Single-pass type I membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
Probable immunoglobulin-like cell surface receptor. On binding with CD47, mediates cell-cell adhesion. Engagement on T-cells by CD47 on antigen-presenting cells results in enhanced antigen-specific T-cell proliferation and costimulates T-cell activation.
Nyati, M.K., et al. Cancer Res. 66(24):11554-11559(2006)van den Berg, T.K., et al. J. Immunol. 175(12):7788-7789(2005)Chen, J., et al. Proc. Natl. Acad. Sci. U.S.A. 99(19):12257-12262(2002)
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