|Other Names||Voltage-dependent calcium channel gamma-1 subunit, Dihydropyridine-sensitive L-type, skeletal muscle calcium channel subunit gamma, CACNG1, CACNLG|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||This protein is a subunit of the dihydropyridine (DHP) sensitive calcium channel. Plays a role in excitation-contraction coupling. The skeletal muscle DHP-sensitive Ca(2+) channel may function only as a multiple subunit complex.|
|Cellular Location||Membrane; Multi-pass membrane protein.|
|Tissue Location||Skeletal muscle.|
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Voltage-dependent calcium channels are composed of fivesubunits. The protein encoded by this gene represents one of thesesubunits, gamma, and is one of two known gamma subunit proteins.This particular gamma subunit is part of skeletal muscle1,4-dihydropyridine-sensitive calcium channels and is an integralmembrane protein that plays a role in excitation-contractioncoupling. This gene is part of a functionally diverse eight-memberprotein subfamily of the PMP-22/EMP/MP20 family and is located in acluster with two family members that function as transmembrane AMPAreceptor regulatory proteins (TARPs).
Chen, R.S., et al. Cell Biochem. Biophys. 47(2):178-186(2007)Chu, P.J., et al. Gene 280 (1-2), 37-48 (2001) :Burgess, D.L., et al. Genomics 71(3):339-350(2001)Burgess, D.L., et al. Genome Res. 9(12):1204-1213(1999)Wagner, T., et al. Cytogenet. Cell Genet. 76 (3-4), 172-175 (1997) :
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