|Other Names||Etoposide-induced protein 24, p53-induced gene 8 protein, Ei24, Pig8|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Acts as a negative growth regulator via p53-mediated apoptosis pathway. Regulates formation of degradative autolysosomes during autophagy (By similarity).|
|Cellular Location||Nucleus membrane; Multi-pass membrane protein. Cytoplasm Endoplasmic reticulum membrane; Multi-pass membrane protein|
|Tissue Location||Found in all the examined tissues. High expression was found in liver, skeletal muscle, pancreas, kidney heart and to a lesser extent in brain, placenta and lung|
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Provided below are standard protocols that you may find useful for product applications.
Ei24 may play a role in the cellular response to DNA damage and/or p53-mediated apoptosis.
Bahk, Y.Y., et al. J. Proteome Res. 9(10):5270-5283(2010)Mork, C.N., et al. FEBS Lett. 581(28):5440-5444(2007)Lee, J., et al. Mol. Cell Proteomics 6(4):669-676(2007)Colombo, E., et al. Mol. Cell. Biol. 25(20):8874-8886(2005)McClive, P.J., et al. Genesis 37(2):84-90(2003)
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