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CPSF2 Antibody (Center) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q9P2I0
Clone Names 5082960
Peptide ID 5082960
Additional Information
Gene ID 53981
Other Names Cleavage and polyadenylation specificity factor subunit 2, Cleavage and polyadenylation specificity factor 100 kDa subunit, CPSF 100 kDa subunit, CPSF2, CPSF100, KIAA1367
Target/Specificity The synthetic peptide sequence used to generate the antibody AP1933a was selected from the Center region of human CPSF2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CPSF2
Synonyms CPSF100, KIAA1367
Function Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. Involved in the histone 3' end pre-mRNA processing.
Cellular Location Nucleus.
Research Areas
Citations (0)

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Background

CPSF2 is a component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition.

References

Beausoleil, S.A., et al., Proc. Natl. Acad. Sci. U.S.A. 101(33):12130-12135 (2004).Hodgman, R., et al., Development 128(14):2815-2822 (2001).de Vries, H., et al., EMBO J. 19(21):5895-5904 (2000).Monsalve, M., et al., Mol. Cell 6(2):307-316 (2000).Takagaki, Y., et al., Mol. Cell. Biol. 20(5):1515-1525 (2000).

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$ 80.00
Cat# BP1933a
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