BCS1L (Center) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q9Y276 |
---|---|
Clone Names | 100712010 |
Gene ID | 617 |
---|---|
Other Names | Mitochondrial chaperone BCS1, h-BCS1, BCS1-like protein, BCS1L, BCS1 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | BCS1L |
---|---|
Synonyms | BCS1 |
Function | Chaperone necessary for the assembly of mitochondrial respiratory chain complex III. Plays an important role in the maintenance of mitochondrial tubular networks, respiratory chain assembly and formation of the LETM1 complex. |
Cellular Location | Mitochondrion inner membrane; Single-pass membrane protein |
Tissue Location | Ubiquitous.. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a homolog of the S. cerevisiae bcs1protein which is involved in the assembly of complex III of themitochondrial respiratory chain. The encoded protein does notcontain a mitochondrial targeting sequence but experimental studiesconfirm that it is imported into mitochondria. Mutations in thisgene are associated with mitochondrial complex III deficiency andthe GRACILE syndrome. Two alternatively spliced transcriptsencoding the same protein have been described. [provided byRefSeq].
References
Moran, M., et al. Hum. Mutat. 31(8):930-941(2010)Gil-Borlado, M.C., et al. Mitochondrion 9(5):299-305(2009)Ramos-Arroyo, M.A., et al. Clin. Genet. 75(6):585-587(2009)Blazquez, A., et al. Neuromuscul. Disord. 19(2):143-146(2009)Tamai, S., et al. J. Cell. Sci. 121 (PT 15), 2588-2600 (2008) :
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.