|Other Names||Coiled-coil domain-containing protein 6, Papillary thyroid carcinoma-encoded protein, Protein H4, CCDC6, D10S170, TST1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Cellular Location||Cytoplasm. Cytoplasm, cytoskeleton. Note=May be a cytoskeletal protein|
|Tissue Location||Ubiquitously expressed.|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a coiled-coil domain-containing protein.The encoded protein is ubiquitously expressed and may function as atumor suppressor. A chromosomal rearrangement resulting in theexpression of a fusion gene containing a portion of this gene andthe intracellular kinase-encoding domain of the ret proto-oncogeneis the cause of thyroid papillary carcinoma.
Leone, V., et al. Oncogene 29(30):4341-4351(2010)Richardson, D.S., et al. Cancer Res. 69(11):4861-4869(2009)Jazdzewski, K., et al. Proc. Natl. Acad. Sci. U.S.A. 105(20):7269-7274(2008)Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)Olsen, J.V., et al. Cell 127(3):635-648(2006)
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