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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   RECQL5 Antibody(Center) Blocking peptide   

RECQL5 Antibody(Center) Blocking peptide

Synthetic peptide

Product Information
Primary Accession O94762
Clone Names 110901100
Peptide ID 110901100
Additional Information
Gene ID 9400
Other Names ATP-dependent DNA helicase Q5, DNA helicase, RecQ-like type 5, RecQ5, RecQ protein-like 5, RECQL5, RECQ5
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms RECQ5
Function Isoform beta is a DNA helicase that plays an important role in DNA replication, transcription and repair. Inhibits elongation of stalled transcripts at DNA damage sites by binding to the RNA polymerase II subunit POLR2A and blocking the TCEA1 binding site. Required for mitotic chromosome separation after cross-over events and cell cycle progress. Required for efficient DNA repair, including repair of inter-strand cross-links. Stimulates DNA decatenation mediated by TOP2A. Prevents sister chromatid exchange and homologous recombination.
Cellular Location Isoform Beta: Nucleus, nucleoplasm. Note=Recruited to sites of DNA damage, such as single-strand breaks and inter-strand cross-links, and at stalled replication forks Isoform Gamma: Cytoplasm.
Tissue Location Ubiquitous.
Research Areas
Citations (0)

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RECQL5 may have an important role in DNA metabolism.


Schwendener, S., et al. J. Biol. Chem. 285(21):15739-15745(2010)Islam, M.N., et al. Mol. Cell. Biol. 30(10):2460-2472(2010)Speina, E., et al. Nucleic Acids Res. 38(9):2904-2916(2010)Aygun, O., et al. J. Biol. Chem. 284(35):23197-23203(2009)Aygun, O., et al. Proc. Natl. Acad. Sci. U.S.A. 105(25):8580-8584(2008)

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$ 80.00
Cat# BP19444c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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