|Other Names||Granulocyte-macrophage colony-stimulating factor receptor subunit alpha, GM-CSF-R-alpha, GMCSFR-alpha, GMR-alpha, CDw116, CD116, CSF2RA, CSF2R, CSF2RY|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Low affinity receptor for granulocyte-macrophage colony- stimulating factor. Transduces a signal that results in the proliferation, differentiation, and functional activation of hematopoietic cells.|
|Cellular Location||Cell membrane; Single-pass type I membrane protein Isoform 4: Secreted.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene is the alpha subunit ofthe heterodimeric receptor for colony stimulating factor 2, acytokine which controls the production, differentiation, andfunction of granulocytes and macrophages. The encoded protein is amember of the cytokine family of receptors. This gene is found inthe pseudoautosomal region (PAR) of the X and Y chromosomes.Multiple transcript variants encoding different isoforms have beenfound for this gene, with some of the isoforms being membrane-boundand others being soluble.
Mirza, S., et al. Biochem. J. 426(3):307-317(2010)Sun, S., et al. Brain Res. 1268, 13-16 (2009) :Suzuki, T., et al. J. Exp. Med. 205(12):2703-2710(2008)Martinez-Moczygemba, M., et al. J. Exp. Med. 205(12):2711-2716(2008)Hansen, G., et al. Cell 134(3):496-507(2008)
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.