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LHX4 Antibody(Center) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q969G2 |
|---|---|
| Clone Names | 100528319 |
| Gene ID | 89884 |
|---|---|
| Other Names | LIM/homeobox protein Lhx4, LIM homeobox protein 4, LHX4 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | LHX4 |
|---|---|
| Function | May play a critical role in the development of respiratory control mechanisms and in the normal growth and maturation of the lung. Binds preferentially to methylated DNA (PubMed:28473536). |
| Cellular Location | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108}. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of a large protein family whichcontains the LIM domain, a unique cysteine-rich zinc-bindingdomain. The encoded protein may function as a transcriptionalregulator and be involved in control of differentiation anddevelopment of the pituitary gland. Mutations in this gene areassociated with syndromic short stature and pituitary and hindbraindefects. An alternative splice variant has been described but itsbiological nature has not been determined.
References
Dateki, S., et al. J. Clin. Endocrinol. Metab. (2010) In press :Castinetti, F., et al. J. Clin. Endocrinol. Metab. 93(7):2790-2799(2008)Pfaeffle, R.W., et al. J. Clin. Endocrinol. Metab. 93(3):1062-1071(2008)Liu, S., et al. Biochem. Biophys. Res. Commun. 366(1):36-41(2008)de Bruijn, D.R., et al. Oncogene 27(5):653-662(2008)
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