|Other Names||PIH1 domain-containing protein 1, Nucleolar protein 17 homolog, PIH1D1, NOP17|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Involved in the assembly of C/D box small nucleolar ribonucleoprotein (snoRNP) particles (PubMed:17636026). Recruits the SWI/SNF complex to the core promoter of rRNA genes and enhances pre-rRNA transcription (PubMed:22368283, PubMed:24036451). Mediates interaction of TELO2 with the R2TP complex which is necessary for the stability of MTOR and SMG1 (PubMed:20864032). Positively regulates the assembly and activity of the mTORC1 complex (PubMed:24036451).|
|Tissue Location||Expressed at low levels in normal mammary epithelial cells (at protein level) (PubMed:24036451). Highest expression in lung, leukocyte and placenta. Expressed at lower levels in brain, prostate, colon, heart, small intestine, liver, ovary, pancreas, skeletal muscle, spleen, testis and thymus (PubMed:21078300).|
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
PIH1D1 belongs to the PIH1 family.
Cloutier, P., et al. Methods 48(4):381-386(2009)McKeegan, K.S., et al. Mol. Cell. Biol. 27(19):6782-6793(2007)Lamesch, P., et al. Genomics 89(3):307-315(2007)Gonzales, F.A., et al. J. Mol. Biol. 346(2):437-455(2005)
If you have any additional inquiries please email technical services at firstname.lastname@example.org.