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MYL12B Antibody(N-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession O14950
Clone Names 100406153
Peptide ID 100406153
Additional Information
Gene ID 103910;10627
Other Names Myosin regulatory light chain 12B, MLC-2A, MLC-2, Myosin regulatory light chain 2-B, smooth muscle isoform, Myosin regulatory light chain 20 kDa, MLC20, Myosin regulatory light chain MRLC2, SHUJUN-1, MYL12B, MRLC2, MYLC2B
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name MYL12B
Synonyms MRLC2, MYLC2B
Function Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Phosphorylation triggers actin polymerization in vascular smooth muscle. Implicated in cytokinesis, receptor capping, and cell locomotion (By similarity).
Tissue Location Ubiquitously expressed in various hematopoietic cells.
Research Areas
Citations (0)

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The activity of nonmuscle myosin II (see MYH9; MIM 160775)is regulated by phosphorylation of a regulatory light chain, suchas MRLC2. This phosphorylation results in higher MgATPase activityand the assembly of myosin II filaments (Iwasaki et al., 2001[PubMed 11942626]).


Martins-de-Souza, D., et al. Eur Arch Psychiatry Clin Neurosci 259(3):151-163(2009)Umeda, D., et al. Biochem. Biophys. Res. Commun. 333(2):628-635(2005)Li, T.B., et al. Acta Biochim. Biophys. Sin. (Shanghai) 36(6):412-418(2004)Webb, R.C. Adv Physiol Educ 27 (1-4), 201-206 (2003) :Iwasaki, T., et al. Cell Struct. Funct. 26(6):677-683(2001)

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$ 80.00
Cat# BP19667a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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