|Other Accession||Q8CHK3, Q0VCY6, NP_001139528.1, NP_001139554.1, NP_001139555.1, NP_077274.3|
|Other Names||Lysophospholipid acyltransferase 7, LPLAT 7, 231-, 1-acylglycerophosphatidylinositol O-acyltransferase, 231n4, Bladder and breast carcinoma-overexpressed gene 1 protein, Leukocyte receptor cluster member 4, Lysophosphatidylinositol acyltransferase, LPIAT, Lyso-PI acyltransferase, Membrane-bound O-acyltransferase domain-containing protein 7, O-acyltransferase domain-containing protein 7, h-mboa-7, MBOAT7, BB1, LENG4, OACT7|
|Target/Specificity||The synthetic peptide sequence is selected from aa 166-180 of HUMAN MBOAT7|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Synonyms||BB1, LENG4, OACT7|
|Function||Acyltransferase which mediates the conversion of lysophosphatidylinositol (1-acylglycerophosphatidylinositol or LPI) into phosphatidylinositol (1,2-diacyl-sn-glycero-3- phosphoinositol or PI) (LPIAT activity). Prefers arachidonoyl-CoA as the acyl donor. Lysophospholipid acyltransferases (LPLATs) catalyze the reacylation step of the phospholipid remodeling pathway also known as the Lands cycle.|
|Cellular Location||Membrane; Multi-pass membrane protein|
|Tissue Location||Overexpressed in metastatic breast and bladder carcinomas relative to normal breast epithelium and urothelium|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the membrane-bound O-acyltransferases family of integral membrane proteins that have acyltransferase activity. The encoded protein is a lysophosphatidylinositol acyltransferase that has specificity for arachidonoyl-CoA as an acyl donor. This protein is involved in the reacylation of phospholipids as part of the phospholipid remodeling pathway known as the Land cycle. Alternative splicing results in multiple transcript variants.
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Lee, H.C., et al. Mol. Biol. Cell 19(3):1174-1184(2008)
Wende, H., et al. Immunogenetics 51 (8-9), 703-713 (2000) :
Fukunaga-Johnson, N., et al. Anticancer Res. 16 (3A), 1085-1090 (1996) :
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