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PRRX2 Blocking Peptide (C-term)

Synthetic peptide

Product Information
Primary Accession Q99811
Other Accession Q06348, NP_057391.1
Additional Information
Gene ID 51450
Other Names Paired mesoderm homeobox protein 2, Paired-related homeobox protein 2, PRX-2, PRRX2, PMX2, PRX2
Target/Specificity The synthetic peptide sequence is selected from aa 238-250 of HUMAN PRRX2
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name PRRX2
Synonyms PMX2, PRX2
Function May play a role in the scarless healing of cutaneous wounds during the first two trimesters of development.
Cellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00108, ECO:0000255|PROSITE-ProRule:PRU00138}
Tissue Location In fetal skin, highest expression found in cells of mesodermal origin within the dermal papilla of the developing hair shaft. Not detected in epidermis or dermis. In adult skin, weakly expressed within the basal layers of the epidermis. Not expressed in dermis.
Research Areas
Citations (0)

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The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins. Expression is localized to proliferating fetal fibroblasts and the developing dermal layer, with downregulated expression in adult skin. Increases in expression of this gene during fetal but not adult wound healing suggest a possible role in mechanisms that control mammalian dermal regeneration and prevent formation of scar response to wounding. The expression patterns provide evidence consistent with a role in fetal skin development and a possible role in cellular proliferation.


Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) :
Eriksson, N., et al. PLoS Genet. 6 (6), E1000993 (2010) :
Tokutomi, Y., et al. Biochem. Biophys. Res. Commun. 364(4):822-830(2007)
Wissmuller, S., et al. Nucleic Acids Res. 34(6):1735-1744(2006)
Gervais, C., et al. Leukemia 19(1):145-148(2005)

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$ 80.00
$ 99.00
Cat# BP19763b
(40 western blots)
Availability: 2 weeks
Bulk Size
Seasonal Special on Bulk Order
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