|Other Accession||Q9R1V3, P97454, NP_005894.3|
|Other Names||Mothers against decapentaplegic homolog 5, MAD homolog 5, Mothers against DPP homolog 5, JV5-1, SMAD family member 5, SMAD 5, Smad5, hSmad5, SMAD5, MADH5|
|Target/Specificity||The synthetic peptide sequence is selected from aa 256-269 of HUMAN SMAD5|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD5 is a receptor-regulated SMAD (R-SMAD).|
|Cellular Location||Cytoplasm. Nucleus. Note=Cytoplasmic in the absence of ligand. Migrates to the nucleus when complexed with SMAD4|
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Provided below are standard protocols that you may find useful for product applications.
Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD5 is a receptor-regulated SMAD (R-SMAD).
Yang, J., et al. Circ. Res. 107(2):252-262(2010)
Tao, S., et al. Dev. Growth Differ. 52(4):335-342(2010)
Middlebrook, B.S., et al. Endocrinology 150(12):5208-5217(2009)
Su, D., et al. J. Biol. Chem. 284(18):12153-12164(2009)
McKnight, A.J., et al. Diabetologia 52(5):844-849(2009)
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