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KRT72 Blocking Peptide(Center)

Synthetic peptide

Product Information
Primary Accession Q14CN4
Other Accession Q148H8, NP_542785.1
Additional Information
Gene ID 140807
Other Names Keratin, type II cytoskeletal 72, Cytokeratin-72, CK-72, Keratin-72, K72, Type II inner root sheath-specific keratin-K6irs2, Type-II keratin Kb35, KRT72, K6IRS2, KB35, KRT6, KRT6IRS2
Target/Specificity The synthetic peptide sequence is selected from aa 328-342 of HUMAN KRT72
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name KRT72
Synonyms K6IRS2, KB35, KRT6, KRT6IRS2
Function Has a role in hair formation. Specific component of keratin intermediate filaments in the inner root sheath (IRS) of the hair follicle (Probable).
Tissue Location Highly expressed in hair follicles from scalp and eyebrow. Also expressed in palmoplantar epidermis. Not expressed in face skin despite the presence of fine hairs histologically. In hair, it is specifically present in the inner root sheath (IRS) of the hair follicle. Present in the IRS cuticle, but not in Henle or Huxley layers of the IRS. In the IRS cuticle, its presence is delayed up to the height of the apex of the dermal papilla (at protein level)
Research Areas
Citations (0)

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Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells. The type II keratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This gene encodes a type II keratin that is specifically expressed in the inner root sheath of hair follicles. The type II keratins are clustered in a region of chromosome 12q12-q13. Multiple transcript variants encoding different isoforms have been found for this gene.


Bertheau, P., et al. PLoS Med. 4 (3), E90 (2007) :
Schweizer, J., et al. J. Cell Biol. 174(2):169-174(2006)
Langbein, L., et al. J. Invest. Dermatol. 120(4):512-522(2003)
Porter, R.M., et al. Br. J. Dermatol. 145(4):558-568(2001)

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$ 80.00
$ 99.00
Cat# BP19811c
(40 western blots)
Availability: 2 weeks
Bulk Size
Seasonal Special on Bulk Order
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