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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   F2 Blocking Peptide (C-term)   

F2 Blocking Peptide (C-term)

Synthetic peptide

Product Information
Primary Accession P00734
Other Accession Q19AZ8, NP_000497.1
Additional Information
Gene ID 2147
Other Names Prothrombin, Coagulation factor II, Activation peptide fragment 1, Activation peptide fragment 2, Thrombin light chain, Thrombin heavy chain, F2
Target/Specificity The synthetic peptide sequence is selected from aa 426-440 of HUMAN F2
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name F2
Function Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing.
Cellular Location Secreted, extracellular space.
Tissue Location Expressed by the liver and secreted in plasma.
Research Areas
Citations (0)

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Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Mutations in F2 leads to various forms of thrombosis and dysprothrombinemia.


Simchen, M.J., et al. Eur. J. Obstet. Gynecol. Reprod. Biol. 153(2):160-164(2010)
Evagelidou, E.N., et al. Diabetes Care 33(11):2468-2470(2010)
Ikejiri, M., et al. Int. J. Hematol. 92(2):302-305(2010)
Fusconi, M., et al. Audiol. Neurootol. 16(3):185-190(2010)
Jacobsen, A.F., et al. J. Thromb. Haemost. (2010) In press :

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$ 80.00
$ 99.00
Cat# BP19825b
(40 western blots)
Availability: 2 weeks
Bulk Size
Seasonal Special on Bulk Order
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