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HBE1 Blocking Peptide(Center)
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P02100 |
|---|---|
| Other Accession | P02103, NP_005321.1 |
| Gene ID | 3046 |
|---|---|
| Other Names | Hemoglobin subunit epsilon, Epsilon-globin, Hemoglobin epsilon chain, HBE1, HBE |
| Target/Specificity | The synthetic peptide sequence is selected from aa 70-83 of HUMAN HBE1 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | HBE1 |
|---|---|
| Synonyms | HBE |
| Function | The epsilon chain is a beta-type chain of early mammalian embryonic hemoglobin. |
| Tissue Location | Red blood cells. |
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Provided below are standard protocols that you may find useful for product applications.
Background
The epsilon globin gene (HBE) is normally expressed in the embryonic yolk sac: two epsilon chains together with two zeta chains (an alpha-like globin) constitute the embryonic hemoglobin Hb Gower I; two epsilon chains together with two alpha chains form the embryonic Hb Gower II. Both of these embryonic hemoglobins are normally supplanted by fetal, and later, adult hemoglobin. The five beta-like globin genes are found within a 45 kb cluster on chromosome 11 in the following order: 5'-epsilon - G-gamma - A-gamma - delta - beta-3'
References
Nuinoon, M., et al. Hum. Genet. (2009) In press :
Tachavanich, K., et al. Southeast Asian J. Trop. Med. Public Health 40(2):306-316(2009)
Naka, I., et al. Biochem. Genet. 46 (11-12), 708-711 (2008) :
Winichagoon, P., et al. Transl Res 152(4):178-184(2008)
Das, B., et al. Ann. Hum. Biol. 35(4):422-431(2008)
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